Blasted Lands is a fairly dangerous area filled with lots of interesting things. There's some great runs, decent gold and good levelling mobs too. And desert mazes. Lots and lots of desert. The important thing to remember when heading into BL is that there is a limited number of ways to recall. You can only recall from Isis if you're devout, but you can always mount bahamut or recall from the fabric dealer or fight your way up to Thoth and solve his riddle. Plenty of run mobs, including Amon, Anhur, Bahamut, Gr'staka, Horus, Ra and Thoth - to name a few.
Walk to the Great Eastern Desert ( 8e, 2se, s, 4se, 2s, sw, w, sw, 2s, 3se, sw, 2w, sw, 2s, e ) and then scan for 'The Entrance to the Blasted Lands' to get from DH to this area (you'll start in the Blasted Lands maze).